Endocrine Abstracts

Introduction: Graves disease is a frequent etiology of hyperthyroidism. It is defined as a diffuse hyperfunctioning of the thyroid gland caused by an autoimmune disorder. We herein present a rare case of unilateral Graves disease involving the right lobe of the thyroid.Observation: A 44-year-old woman was referred for investigation of subclinical hyperthyroidism revealed by a routine check-up. On physical examination, she had tremor, eyelid retraction, t...

Introduction: Thyrotoxicosis is an uncommon cause of cholestasis. It’s a diagnostic challenge considering the broad differential diagnosis. Herein we report a case of Grave’s disease revealed by severe cholestatic jaundice.Observation: A 46 old male with a history of Sickle cell disease complained of diarrhea and significant weight loss for eight months, followed the last month by palpitations, heat intolerance, anxiety, insomnia and progressiv...

Introduction: Pheochromocytomas are rare catecholamine-secreting tumors presenting with various clinical manifestations. Hypertension is the most common finding in pheochromocytomas. It can be either persistent or paroxysmal. Study Design: We conducted a retrospective study of 34 patients who were admitted into the endocrinology department of Charles Nicolle hospital, with a diagnosis of a pheochromocytoma from January 2005 to November 2022.Results: Twen...

Introduction: Pheochromocytomas are rare, mostly benign catecholamine-producing neuroendocrine tumors. Clinical manifestations are heterogenous, including persistent or paroxysmal hypertension, sweating, palpitation and headaches known as Menard triad. Diagnostic approach is based on demonstration of catecholamine excess and tumor localization. Our study aimed to describe clinico-biological and radiological features of pheochromocytomas.Methods: We condu...

Introduction: Excessive production of growth hormone (GH) in acromegaly is most commonly caused by a somatotroph pituitary adenoma. The therapeutic arsenal is based on selective transsphenoidal adenomectomy (STA) as a first-line treatment. The aim of our study was to determine predictive factors of postoperative biochemical remission in acromegalic patients.Methods: We conducted a retrospective study including 18 acromegalic patients followed-up in the e...

Introduction: Acromegaly is a rare condition secondary to the hypersecretion of GH, often by a pituitary adenoma, which can lead to hypopituitarism of varying degrees. Our study aimed to analyze the characteristics of pituitary insufficiency during acromegaly and to search for its predictive factors.Methods: Retrospective study carried out in the endocrinology department of Charles Nicolles Hospital. We recorded 28 patients with acromegaly over a period ...

Introduction: The management of acromegaly is commonly based on selective transsphenoidal adenomectomy (STA) as a first-line treatment, and other therapeutic options including somatostatin analogues (SA), dopamine agonists (DA) and radiotherapy as second-line treatment or in case of operative contraindications. The aim of our study was to assess the remission rate and to determine the predictive factors for long-term remission in acromegalic patients.Met...

Introduction: Somatotropin macroadenomas are associated with a considerable risk of ophthalmological impairment. The aim of our study was to determine the prevalence of ophthalmological complications and their associated factors in patients with acromegaly.Methods: We conducted a retrospective study including 28 patients with somatotropin adenomas and followed in the endocrinology department of Charles Nicolle Hospital. Clinical, biochemical and imaging ...

Introduction: Acromegaly results from an autonomous hypersecretion of growth hormone (GH) typically by a pituitary adenoma, commonly revealed by a dysmorphic syndrome. The aim of our study was to describe clinico-biological and radiological features of acromegaly.Methods: We conducted a retrospective study including 28 patients with acromegaly followed in the endocrinology department of Charles Nicolle Hospital. Clinical, biochemical, ophthalmological an...

High blood pressure of endocrine origin remains a rare cause of hypertension. The interest of the research of endocrine hypertension lies in the severity of certain forms and its potentially curable and reversible nature, hence the interest of oriented screening. The aim of our work was to study the profile of endocrine hypertension among a population suffering from secondary diabetes. This is a retrospective descriptive study of 55 patients followed in endocrinology departmen...